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研究実績

Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H.
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.
Cell. . 154(5):1112-26.,2013 Aug 29.

Nishimura T, Kaneko S, Kawana-Tachikawa A, Tajima Y, Goto H, Zhu D, Nakayama-Hosoya K, Iriguchi S, Uemura Y, Shimizu T, Takayama N, Yamada D, Nishimura K, Ohtaka M, Watanabe N, Takahashi S, Iwamoto A, Koseki H, Nakanishi M, Eto K, Nakauchi H.
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation.
Cell Stem Cell. . 12(1):114-26,.2012.11.

Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL.
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.
Cell.. 148(5):1001-14.,2012 .

Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H.
Nonmyelinating schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
Cell.. 147(5):1146-58., 2011 Nov 23.

Kobayashi T, Yamaguchi T, Hamanaka S, Kato-Itoh M, Yamazaki Y, Ibata M, Sato H, Lee YS, Usui J, Knisely AS, Hirabayashi M, Nakauchi H.
Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells.
Cell. 142:787-99,Sep 2010.

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

Morita Y, Ema H, Nakauchi H.
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment.
J Exp Med. . 207:1173-1182,April 2010.

Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.

Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP.
Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.
Cell Cycle. 9(6).: 1051 - 1056,2010 Mar 23.

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