研究実績

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Takayama N, Eto K, Nakauchi H.
Potential usefulness of human iPS cells on the generation of platelets
Nihon Rinsho.. :,2011 Dec.

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Kobayashi T, Nakauchi H.
From cell therapy to organ regeneration therapy: generation of functional organs from pluripotent stem cells
Nihon Rinsho.. :,2011 Dec.

Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.

Umeyama K, Saito H, Kurome M, Matsunari H, Watanabe M, Nakauchi H, Nagashima H.
Characterization of the ICSI-mediated gene transfer method in the production of transgenic pigs.
Mol Reprod Dev.. :218-28,2011 Dec 29..

Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H.
Nonmyelinating schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
Cell.. 147(5):1146-58., 2011 Nov 23.

Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S.
Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL.
Exp Hematol. . :,2011 Nov 17..

Umemoto T, Yamato M, Ishihara J, Shiratsuchi Y, Utsumi M, Morita Y, Tsukui H, Terasawa M, Shibata T, Nishida K, Kobayashi Y, Petrich BG, Nakauchi H, Eto K, Okano T.
Integrin αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells.
Blood. . :, 2011 Nov 16. .

Nishimura S, Manabe I, Nagasaki M, Kakuta S, Iwakura Y, Takayama N, Ooehara J, Otsu M, Kamiya A, Petrich B, Urano T, Kadono T, Sato S, Aiba A, Yamashita H, Sugiura S, Kadowaki T, Nakauchi H, Eto K, Nagai R.
In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling.
Blood. . :,2011 Nov 16..

Okaji Y, Tashiro Y, Gritli I, Nishida C, Sato A, Ueno Y, Del Canto Gonzalez S, Ohki-Koizumi M, Akiyama H, Nakauchi H, Hattori K, Heissig B.
Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis.
Exp Hematol. . :, 2011 Nov 3..

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Watanabe M, Kurome M, Matsunari H, Nakano K, Umeyema K, Shiota A, Nakauchi H, Nagashima H.
The creation of transgenic pigs expressing human proteins using BAC-derived, full-length genes and intracytoplasmic sperm injection-mediated gene transfer.
Transgenic Res. . :,2011 Oct 25..

Watabe Y, Baba Y, Nakauchi H, Mizota A, Watanabe S.
The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells.
Biochem Biophys Res Commun. . :415(1):42-7., 2011 Nov 11.

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Ishihara M, Nishida C, Tashiro Y, Gritli I, Rosenkvist J, Koizumi M, Okaji Y, Yamamoto R, Yagita H, Okumura K, Nishikori M, Wanaka K, Tsuda Y, Okada Y, Nakauchi H, Heissig B, Hattori K.
Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b(+)/F4/80(+) myeloid cell recruitment.
Leukemia. . :,2011 Sep 20..

Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.

Saito R, Nakauchi H, Watanabe S.
Serine/threonine kinase, Melk, regulates proliferation and glial differentiation of retinal progenitor cells.
Cancer Sci. . :,2011 Sep 16..

Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R, Sato Y, Sato-Otsubo A, Kon A, Nagasaki M, Chalkidis G, Suzuki Y, Shiosaka M, Kawahata R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Ishiyama K, Mori H, Nolte F, Hofmann WK, Miyawaki S, Sugano S, Haferlach C, Koeffler HP, Shih LY, Haferlach T, Chiba S, Nakauchi H, Miyano S, Ogawa S.
Frequent pathway mutations of splicing machinery in myelodysplasia.
Nature.. 478: 64–69, 2011 Sep 11.

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Okada K, Kamiya A, Ito K, Yanagida A, Ito H, Kondou H, Nishina H, Nakauchi H.
Prospective isolation and characterization of bi-potent progenitor cells in early mouse liver development.
Stem Cells Dev. . :,2011 Aug 23.

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Hamanaka S, Yamaguchi T, Kobayashi T, Kato-Itoh M, Yamazaki S, Sato H, Umino A, Wakiyama Y, Arai M, Sanbo M, Hirabayashi M, Nakauchi H.
Generation of germline-competent rat induced pluripotent stem cells.
PLoS One. :, 2011 Jul 15.

Kawahara M, Chen J, Sogo T, Teng J, Otsu M, Onodera M, Nakauchi H, Ueda H, Nagamune T.
Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera
Cytokine. Volume 55:Pages 402-408,September 2011.

Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.

Yokoi T, Kobayashi H, Shimada Y, Higuchi T, Eto Y, Ishige N, Kitagawa T, Otsu M, Nakauchi H, Ida H, Ohashi T.
Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease.
J Gene Med. . :,2011 Apr 25.

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Onozuka I, Kakinuma S, Kamiya A, Miyoshi M, Sakamoto N, Kiyohashi K, Watanabe T, Funaoka Y, Ueyama M, Nakagawa M, Koshikawa N, Seiki M, Nakauchi H, Watanabe M.
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Biochem Biophys Res Commun. . 406(1):134-40,2011 Mar 4.

Tanimura S, Tadokoro Y, Inomata K, Binh NT, Nishie W, Yamazaki S, Nakauchi H, Tanaka Y, McMillan JR, Sawamura D, Yancey K, Shimizu H, Nishimura EK.
Hair follicle stem cells provide a functional niche for melanocyte stem cells.
Cell Stem Cell. . 8(2):177-87.,2011 Feb 4.

Morita Y, Iseki A, Okamura S, Suzuki S, Nakauchi H, Ema H.
Functional characterization of hematopoietic stem cells in the spleen.
Exp Hematol. . 39(3):351-359.,2011 Mar.

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