研究実績

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Ema H. Morita Y. Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H.
Adult mouse hematopoietic stem cells: purification and single-cell assays.
Nature Protocols. 1:2979-87,2006.

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Oguro H, Iwama A, Morita Y, Kamijo T, van Lohuizen M, Nakauchi H.
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice.
J Exp Med. 203:2247-53,2006.

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Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M, Okuda A.
Putative "stemness" gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells.
Mol Cell Biol.. 26:6557-70,2006.

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Yamazaki S, Iwama A, Takayanagi S, Morita Y, Eto K, Ema H, Nakauchi H.
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematpoetic stem cells.
EMBO J. 25:3515-3523,2006.

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Morita Y, Ema H, Yamazaki S, Nakauchi H.
Non - sicde-population hematopoietic stem cells in mouse bone marrow.
Blood. 108:2850-2856,2006.

Side p opulation purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties.

Chiba T, Kita K, Zheng YW, okosuka O, Saisho H, Iwama S, Nakauchi H, Taniguchi H.
Side p opulation purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties.
Hepatology. 44:240-51,2006.

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Furuta C, Ema H, takayanagi S, ogaeri T, Okamura D, Matsui Y, Nakauchi H.
Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo.
Development. 133:2771-9,2006.

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Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H.
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.
Proc Natl Acad Sci U S A. 103:7112-7,2006.

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Takayanagi SI, Hiroyama T, Yamazaki S, Nakajima T, Morita Y, Usui J, Eto K, Motohashi T, Shiomi K, Keino-Masu K, Masu M, Oike Y, Mori S, Yoshida N, Iwama A, Nakauchi H.
Genet ic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell-surface protein with the thrombospondin-1 domain.
Blood. 107:4317-25,2006.

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Nabekura T, Otsu M, Nagasawa T, Hakauchi H, Onodera M.
Potent Vaccine Therapy with Dendritic Cells Genetically Modified by the Gene-Silencing-Resistant Retroviral Vector GCDNsap.
Molecular Therapy. 13:301-09,2006.

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