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研究実績

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Doki, N., Kitaura, J., Inoue, D., Kato, N., Kagiyama, Y., Uchida, T., Togami, K., Isobe, M., Ito, S., Maehara, A., Izawa, K., Oki, T., Harada, Y., Nakahara, F., Harada, H., and Kitamura, T.
Fyn is not essential for Bcr-Abl-induced leukemogenesis in mouse bone marrow transplantation models.
Int. J. Hematol.. 95(2):167-175.,2012.

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Oki, T., Kitaura, J., Watanabe-Okochi, N., Nishimura, K., Maehara, A., Uchida, T., Komeno, Y., Nakahara, F., Harada, Y., Sonoki, T., Harada, H., and Kitamura, T.
Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis.
Leukemia. :in press,2012.

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Tran, P.T., Bendapaudi, P.K., Lin, H.J., Choi, P., Koh, S., Chen, J., Horng, G., Hughs, N.P., Schwartz, L.H., Miller, J.H., Kawashima, T., Kitamura, T., Paik, D., and Felsher, D.W.
Survival and death signals can predict tumor response to therapy after oncogene inactivation.
Science Translational Medicine. Vol. 3, Issue 103:103ra99 ,2011.

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Nakamura, M., Kitaura, J., Enomoto, Y., Lu, Y., Nishimura, K., Isobe, M., Ozaki, K., Komeno, Y., Nakahara, F., Oki, T., Kume, H., Homma, Y., and Kitamura, T.
TSC-22 is a negative-feedback regulator of Ras/Raf signaling: Implications for tumorigenesis.
Cancer Science. 103(1):26-33.,2012.

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Suzuki, K., Ono, R., Ohishi, K., Masuya, M., Kataoka, I., Liu, B., Nakamori, Y., Ino, K., Monma, F., Hamada, H., Kitamura, T., Katayama, N., and Nosaka, T. (2012) IKAROS isoform 6 enhances BCR-ABL-mediated proliferation of human CD34+ hematopoietic cells on stromal cells.
IKAROS isoform 6 enhances BCR-ABL-mediated proliferation of human CD34+ hematopoietic cells on stromal cells.
Int J Oncology. 40(1):53-62.,2012.

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Shibata-Minoshima, F., Oki, T., Doki, N., Nakahara, F., Kageyama, S., Kitaura, J., Fukuoka, J. and Kitamura, T.
Identification of RHOXF2 (PEPP2) as a cancer-promoting gene by expression cloning.
Int J Oncology. 40(1):93-98.,2012.

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Kawamura, S., Sato, I., Wada, T., Yamaguchi, K., Li, Y., Li, D., Zhao, X., Ueno, S., Aoki, H., Tochigi, T., Kuwahara, M., Kitamura, T., Takahashi, K., Moriya, S., and Miyagi, T.
Plasma membrane-associated sialidase (NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signaling.
Cell Death and Differentiation. 19(1):170-179.,2012.

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Yoshimi, Y., Goyama, S., Watanabe-Okochi, N., Yoshiki, Y., Nannya, Y., Nitta, E., Arai, S., Sato, T., Shimabe, M., Nakagawa, M., Imai, Y., Kitamura, T. and Kurokawa, M.
Evi1 represses PTEN expression by interacting with polycomb complexes and activates PI3K/AKT/mTOR signaling.
Blood. 117:3617-3628.,2011.

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Kato, N., Kitaura, J., Doki, N., Komeno, Y., Watanabe-Okochi N., Togami, K., Nakahara, F., Oki, T., Enomoto, Y., Fukuchi, Y., Nakajima, H., Harada, Y., Harada, H., and Kitamura. T.
Two types of C/EBPa mutations play distinct roles in leukemogenesis: Lessons from clinical data and BMT models.
Blood. 117(1):221-233.,2011.

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Enomoto, Y., Kitaura, J., Hatakeyama, K., Watanuki, J., Akasaka, T., Kato, N., Shimanuki, M., MNishimura, K., Takahashi, M., Taniwaki, M., Haferlach, C., Siebert, R., Dyer, M.J.S., Asou, N., Aburatani, H., Nakakuma, H., *Kitamura, T., and *Sonoki, T.
Eμ/miR-125b transgenic mice develop lethal B-cell malignancies
Leukemia. 25(12):1849-56.,2011 .

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東京大学医科学研究所 幹細胞治療研究センターについて
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東京大学医科学研究所 幹細胞治療研究センター 幹細胞シグナル制御分野 〒108-8639 東京都港区白金台4-6-1 Tel:03-5449-5759 Fax:03-5449-5760 kitamura(at)ims.u-tokyo.ac.jp

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